Aplasia cutis congenita: a rare extensive bilateral case of extremities

Aplasia cutis congenital is a rare congenital absence of skin, exceptionally involves extremities. Most cases are sporadic but familial autosomal dominant pattern can be found. The etiology remains unclear, both genetic and environmental causes have been implicated. This lesion has primarily a clinical diagnosis. Imaging studies may be used to evaluate underlying tissues and investigate other comorbid abnormalities. Treatment modalities depend upon the extent defect and involvement of underlying tissues. Genetic counseling is useful in cases of hereditary form. We report a new case of extensive bilateral aplasia cutis congenital of extremities in a new born, occurred as an isolated sporadic case without family history, no teratogenic medication and no evidence for an amniotic band or infection in pregnancy.